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Other outcomes showed no significant differences

Patients should be counseled to report severe abdominal pain (potential pancreatitis), right upper quadrant pain (possible gallbladder disease), visual changes (especially with diabetic retinopathy), persistent nausea or vomiting, or signs of dehydration which may increase risk of acute kidney injury

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Link Maczurek, A., Hager, K., Kenklies, M., et al

For brain-targeting compounds, where the goal is modulating delicate neurotransmitter systems and growth factor pathways, impurities are not just unwanted, they are potentially dangerous